Cover of Akins et al., 2024
Modified from Swift et al., 2023
Modified from Auchampach et al., 2022
Cover of Patterson and Swift, 2019
Select publications. Teal name indicates Patterson Lab member.
2024
Swift SK, Purdy AL, Patterson M. Protocol for quantifying murine cardiomyocyte cell division by single-cell suspension. STAR Protocols, 2024 PMID: 39520685
Swift SK, Purdy AL, Buddell T, Lovett JJ, Chanjeevaram SV, Arkatkar A, O'Meara CC, Patterson M. A broadly applicable method for quantifying cardiomyocyte cell division identifies proliferative events following myocardial infarction. Cell Reports Methods, 2024. PMID: 39255794
Gural B, Kirkland L, Hockett A, Sandroni P, Zhang J, Rosa-Garrido M, Swift SK, Chapski D, Flinn MA, O'Meara CC, Vondriska TM, Patterson M, Jensen BC. Novel Insights into Post-Myocardial Infarction Cardiac Remodeling through Algorithmic Detection of Cell-Type Composition Shifts. Preprinted BioRxiv, 2024. PMID: 39149394
Akins KA, Flinn MA, Swift SK, Chanjeevaram SV, Purdy AL, Buddell T, Kolell ME, Andresen KG, Paddock S, Buday SL, Veldman MB, O'Meara CC, Patterson M. Runx1 is sufficient but not required for cardiomyocyte cell-cycle activation. AJP Heart and Circulatory Physiology, 2024. PMID: 38847758
Buddell T, Purdy AL, Patterson M. The genetics of cardiomyocyte polyploidy. Current Topics in Developmental Biology, 2024. PMID: 38556425
Alvarez-Argote S, Almeida VA, Knas MC, Buday SL, Patterson M, O’Meara CC. Global IL4Ra blockade exacerbates heart failure after an ischemic event in mice and humans. AJP Heart and Circulatory Physiology, 2024. PMID: 38426866
Alvarez-Argote S, Paddock SJ, Flinn MA, Moreno CW, Knas MC, Almeida VA, Buday SL, Bakhshian Nik A, Patterson M, Chen YG, Lin CW, O’Meara CC. Interleukin 13 promotes functional recover after myocardial infarction via direct signaling to macrophages. JCI Insight, 2024. PMID: 38051583
2023
Purdy AL*, Swift SK*, Sucov HM, Patterson M. Tnni3k influences cardiomyocyte S-phase and proliferation. Journal of Molecular and Cellular Cardiology, 2023. PMID: 37597489
*co-first authors
Flinn MA, Alvarez-Argote S, Knas MC, Almeida VA, Paddock SJ, Zhou X, Jamal A, Taylor R, Liu P, Drnevich J, Patterson M. Link BA, O’Meara CC. Myofibroblast Ccn3 is regulated by Yap and Wwtr1 and contributes to adverse cardiac outcomes. Frontiers in Cardiovascular Medicine. 2023 PMID: 36998974
Swift SK, Purdy AL, Kolell ME, Andresen KG, Lahue C, Buddell T, Akins KA, Rau CD, O'Meara CC, Patterson M. Cardiomyocyte ploidy is dynamic during postnatal development and varies across genetic backgrounds. Development, 2023 Apr. PMID: 36912240
Sam and Michaela are interviewed by Development: The people behind the papers.
2022
Auchampach J, Han L, Huang GN, Kühn B, Lough JW, O'Meara CC, Payumo AY, Rosenthal NA, Sucov HM, Yutzey KE, Patterson M. Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration. AJP Heart and Circulatory Physiology, 2022. PMID: 35179974
Wang X, Wan TC, Lauth A, Purdy AL, Kulik KR, Patterson M, Lough JW, Auchampach JA. Conditional depletion of the acetyltransferase Tip60 protects against the damaging effects of myocardial infarction. Journal of Molecular and Cellular Cardiology, 2022. PMID: 34610340
2021
Paddock SJ, Swift SK, Alencar-Almeida V, Kenarsary A, Alvarez-Argote S, Flinn MA, Patterson M, O'Meara CC. IL4Rα signaling promotes neonatal cardiac regeneration and cardiomyocyte cell cycle activity. Journal of Molecular and Cellular Cardiology, 2021. PMID: 34343540
Wang X, Lupton C, Lauth A, Wan TC, Foster P, Patterson M, Auchampach JA, Lough JW. Evidence that the acetyltransferase Tip60 induces the DNA damage response and cell-cycle arrest in neonatal cardiomyocytes. Journal of Molecular and Cellular Cardiology, 2021. PMID: 33609538
2020
Patterson M. Introductions to the Community: Early-Career Researchers in the Time of COVID-19.
Cell Stem Cell, 2020. PMID: 32619510
Gan P, Patterson M, Watanabe H, Wang K, Edmonds RA, Reinholdt LG, Sucov HM. Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy. Scientific Reports., 2020. PMID: 32371981
Shen H, Gan P, Wang K, Darehzereshki A, Wang K, Kumar SR, Lien CL, Patterson M, Tao G, Sucov HM. Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling. Elife, 2020. PMID: 32167474
Gan P, Patterson M, Sucov HM. Cardiomyocyte Polyploidy and Implications for Heart Regeneration. Annual Review of Physiology, 2020. PMID: 31585517
2019
Patterson M, Swift SK. Residual Diploidy in Polyploid Tissues: A Cellular State with Enhanced Proliferative Capacity for Tissue Regeneration? Stem Cells and Development, 2019. PMID: 31608782
Gan P, Patterson M, Velasquez A, Wang K, Tian D, Windle JJ, Tao G, Judge DP, Makita T, Park TJ, Sucov HM. Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency. PLoS Genetics, 2019 PMID: 31589606
2017
Patterson M, Barske L, Van Handel B, Rau CD, Gan P, Sharma A, Parikh S, Denholtz M, Huang Y, Yamaguchi Y, Shen H, Allayee H, Crump JG, Force TI, Lien CL, Makita T, Lusis AJ, Kumar SR, Sucov HM. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genetics, 2017. PMID: 28783163